Postdoc Fellow-Computational Biology-Immuno Oncology

San Diego , CA
United States
Life Sciences

Summary/Scope

 

We are seeking an experienced T-cell immunologist to investigate the role of PD-1 in T cell and Treg biology in the context of autoimmune diseases and understand the mechanism of action of therapeutics targeting this pathway. The successful applicant will have a strong background and publication record in immunology with a preference to a background in T-cell immunology. The applicant will be able to design and execute a variety of routine in vitro functional assays such as proliferation, cytokine secretion, T-reg assays, co-culture assays to measure cytotoxicity, and in-depth characterization of immune phenotype by flow cytometry to understand biology of pathways of interest. The applicant will also be working with in vivo models to understand the biological role of this pathway in various disease settings. The successful candidate will have the opportunity to work closely with discovery project teams and scientists and to present his or her work at project team meetings and to the senior research leadership. Industry experience is preferred but not essential.

 

Responsibilities will include, but are not limited to, the following:

  • Plan and execute experiments independently
  • Stay current with the literature in order to design experiments that address biological questions
  • Analyze, interpret and present scientific data
  • Interact with drug development team members to design experiments that can address mechanistic questions for the therapeutic of interest
  • Accurately maintain data and reports

 

Skills/Knowledge Required:

  • Highly motivated scientist
  • PhD with 1-2 years of experience. PhD completed within last 3 years.
  • A deep understanding of T cell biology and general immunology
  • Experience with primary immune cell based assays, experience with T cell based assays, multiparameter flow cytometry, and molecular techniques
  • Experience with in vivo studies in disease or mechanistic models
  • Excellent communication, presentation and organizational skills

Please send resume and cover letter to Kassie Dumas at [email protected]

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